Mephenesin and Meprobamate -Propandiol Derivatives

Mephenesin

Mephenesin acts by decreasing the transmission in polysynaptic pathway. It produces muscle relaxant effects. It can be used in:

1. Strychnine over dosage

2. Convulsions

Adverse effects include sedation and drowsiness.

Dose is 1-3 grams daily in divided doses.

Meprobamate

Meprobamate is less commonly used because of strong sedative effects which hinders normal activities of individual. It is an enzyme inducer and can interact with various drugs.

It is contraindicated in porphyria.

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