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Role of chemotherapy
- As primary curative therapy.
- As adjuvant treatment.
- As neo adjuvant treatment.
- As palliative chemotherapy for advanced disease.
OBJECTIVES
b) Hodgkin’s disease
c) Testicular tumours
d) Gestational trophoblastic diseases
e) Small cell carcinoma
f) Ewing sarcoma
g) Osteo sarcoma
NEO ADJUVANT CHEMOTHERAPY ( to downstage the tumour and make organ and limb saving surgery possible)
a) Osteo sarcoma
b) Carcinoma breast
c) Colorectal cancers
d) Head and neck cancers
ADJUVANT CHEMOTHERAPY
( for prevention of recurrence after surgery)
a) Carcinoma breast
b) Colorectal cancers
c) Carcinoma ovary
d) Carcinoma lung
e) Head and neck cancers
f) Osteo sarcoma
PALLIATIVE CHEMOTHERAPY It is used in advanced and incurable cancers to slow down the progress of disease and to achieve pain control
COMMON CANCERS
PROSTATE / BREAST
LUNG
COLORECTAL
BLADDER / UTERUS / OVARY
NHL
MELANOMA
HEAD & NECK
KIDNEY
PANCREAS
CURABLE CANCERS IN ADVANCED STAGE
- NON HODGKIN’S LYMPHOMA
- HODGKIN’S DISEASE
- ACUTE LEUKAEMIA
- HAIRY CELL LEUKAEMIA
- GERM CELL TUMOURS
- GASTATIONAL TROPHOBLASTIC DISEASE
- PAPILLARY & FOLLICULAR CA THYROID
CHEMOTHERAPY DRUGS
First line and commonly used drugs to be made available so as to start treatments immediately after diagnosis
Drug groups
- First line and commonly used drugs to be made available so as to start treatments immediately after diagnosis
- agents (cyclophosphamide)
- Antimetabolites (methotrexate)
- Antitumour antibiotics (bleomycin)
- Mitotic spindle agents (taxols)
- Topoisomerse inhibitors (etoposide)
- Others (l- asparaginase)
- Hormones: (steroids, ER blockers etc)
RADIATION
MODE OF RADIATION
1. TELETHERAPY(ERBT)
2. BRACHYTHERAPY
3. 3D – CRT / IMRT
4. GAMMA KNIFE RADIOSURGERY
5. CYBERKNIFE
OBJECTIVES OF RADIATION
1. CURATIVE
2. CONSOLIDATION
3. MEO ADJUVANT
4. ADJUVANT
5. PALLIATIVE
FIELDS OF RADIATION
1. INVOLVED FIELD(IF)
2. EXTENDED FIELD(EF)
3. MENTAL FIELD(MF)
4. INVERTED Y
5. DOG LEG
