howMed Know Yourself
Fondaparinux Chemistry – synthetic pentasacchride Mechanism of Action Acts by inhibiting factor X. Pharmacokinetics Long half life of 17-21 hours. … Read More »
Heparin
History Heparin is commonly administered anticoagulant in emergency. It was discovered in 1912 by a medical student at John Hopkins … Read More »
Anticoagulants
Hemostasis The mechanisms involved to stop bleeding are known as hemostasis. This includes four processes: Vasoconstriction Platelet plug formation Coagulation/Clot … Read More »
Myeloid and Megakaryocytic Growth Factors
Myeloid growth factors Granulocyte colony stimulating factor (G – CSF) – Filgrastim Granulocyte macrophage colony stimulating factor (GM – CSF) … Read More »
Erythropoietin
Erythropoietin is a glycosylated protein produced by peritubular cells of kidney. It is essential for normal reticulocyte production. Stimulus Stimulus … Read More »
Folic Acid (Vitamin B9 or Pterylglutamic acid)
Folic acid is composed of 3 subunits Pteridine Para aminobenzoic acid Glutamic acid residues –attached to pteryl portion forming monoglutamate, … Read More »
Vitamin B12
Complex cobalt containing molecule to which various groups are linked covalently to form cobalamine. These include: Endogenous cobalamines –include methyl … Read More »
Iron as Haematinic Agent
Haematinics are the agents used for formation of blood to treat various types of anemias. These include: Iron Vitamin B12 … Read More »
Drugs Acting on Renin Angiotensin System
Drugs acting on renin angiotensin system are: ACE inhibitors Angiotensin receptor blockers Angiotensin Converting Enzyme (ACE) Inhibitors Enalapril is a … Read More »
Calcium – Channel Blockers as Antihypertensive Drugs
There are two types of calcium channels: Voltage gated Receptor operated Type of Voltage gated Calcium Channels Voltage gated channels … Read More »