howMed Know Yourself
Direct acting selective alpha 1 agonist. Pharmacological Actions Eye mydriasis CVS –Increased TPR, Increased blood pressure Respiratory mucosal vasoconstriction and … Read More »
Amphetamines
Amphetamines are indirectly acting. They act more powerfully on the CNS because in addition to noradrenaline, other biogenic amines are … Read More »
Ephedrine
Ephedrine has mixed actions Source Natural ephedra plant. It can also be synthesized synthetically. Mechanism of Action Stimulates both alpha … Read More »
Dobutamine
Receptor selectivity β1>β2>>>>α Dobutamine has a greater affinity for beta 1 receptors. It produces greater ionotropic effect than chronotropic effect. … Read More »
Dopamine
The effect of dopamine on various receptors is concentration dependent D1=D2>>β>>α At lower concentration, only dopamine receptors are stimulated. At … Read More »
Isoprenaline
Heavier the substitution on amino radical, greater is the beta activity. Isopropyl or propyl substitution in isoprenaline basically acts only … Read More »
Noradrenaline
Receptor sensitivity in noradreanline is α1=α2, β1>>β2 Thus its actions are somewhat different from that of adrenaline. Pharmacological Actions … Read More »
Adrenaline
Adrenaline is a prototypical sympathomimetic drug (used as a template against which other drugs are compared); this is because it … Read More »
Sympathomimetics
Symphathomimetics mimic the effects of sympathetic system. Two types of receptors are present: Alpha receptors Beta receptors All sympathomimetics act … Read More »
Autonomic Nervous System –An Introduction
The central nervous system is divided into: Somatic system –voluntary Autonomic system –involuntary Autonomic nervous system is further classified into … Read More »