howMed Know Yourself
Unit volume of blood which is cleared off a drug per unit time is known as clearance. Clearance is not … Read More »
Excretion of Drug
When drugs are taken in, they should be eliminated as well, as we do not want their action to continue … Read More »
Elimination of Drug
The irreversible shift of a drug from one part of the body to other part of system is known as … Read More »
Factors affecting Biotransformation
Biotransformation is significantly affected by a number of factors, these include: 1. Enzyme Induction: When drugs given over prolonged period … Read More »
Prodrugs
Prodrugs contain parent drug compounds in inactive form. Active specie is required to be carried to the site of action. … Read More »
Biotransformation of Xenobiotics
“Enzymatic modification of the drug occurring within the living organisms or chemical transformation a drug goes through in living organisms … Read More »
Plasma Half Life of Drugs
Onset, duration and intensity of effect of drug depends on the rate of absorption, distribution and elimination (biotransformation, excretion). In … Read More »
Bioavailability of Drugs
Fraction of the dose of a drug contained in any dosage form that reaches the systemic circulation in unchanged or … Read More »
Distribution of Drugs
Drug enters the body by absorption. Inside the body, drugs move in the blood to different parts of the body. … Read More »
Factors affecting Absorption of Drugs
The factors affecting absorption of drugs are related both to the drugs and to the body. Factors Related to Drugs: … Read More »