howMed Know Yourself
Alpha and beta blockers block alpha 1, beta 1 and beta 2 receptors, while act as partial agonist at beta … Read More »
Antihypertensive Drugs
Hypertension WHO defines hypertension as: “Level of systolic blood pressure more than 140 mmHg and diastolic blood pressure more than … Read More »
Osmotic Diuretics
Mannitol is the most commonly used osmotic diuretic. It is given I/V and not orally as it might produce diarrhea. … Read More »
Potassium Sparing Diuretics
Potassium sparing diuretics act on the collecting tubule. Chemistry Eplerenone is more selective for aldosterone receptors. Canrenone is an active … Read More »
Thiazide Diuretics
Thiazide diuretics are also known as NaCl symporter inhibitors. Thiazide diuretics act on the distal convoluted tubule. They were discovered … Read More »
Loop Diuretics
Loop diuretics are also known as high ceiling diuretics or Na+K+2Cl- cotransporter inhibitors. Loop diuretics act at the ascending thick … Read More »
Carbonic Anhydrase Inhibitors
Carbonic anhydrase inhibitors act on the proximal convoluted tubule. Drugs Acetazolamide Dorzolamide Brinzolamide Dorzolamide and Brinzolamide are used topically for … Read More »
Diuretics
Diuretics are the drugs which increase urinary flow. Clinically all drugs used concomitantly increase Na+ excretion and accompanying anion, mostly … Read More »
Potassium Channel Openers
Nicorandil acts in three ways: Releases NO leading to vasodilatation, decreasing preload and afterload Hyperpolarization, leading to relaxation of blood … Read More »
Calcium Channel Blockers in Ischemic Heart Disease
Only drugs which block L type of channels, which are large in conductance are effective. Nifedipine has different binding sites … Read More »