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Pharmacology

Drug Dependence

Definition The WHO defines drug dependence as: “A state, psychic and sometimes  physical resulting  from taking a drug characterized by …

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Adverse Drug Effects

Undesirable or harmful effects which can occur at therapeutic doses and need a reduction of dose or drug withdrawal. Adverse …

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Factors Modifying Action of Drugs

A multitude of host & environmental factors influence drug response. Understanding of these factors can guide choice of appropriate drug …

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Mechanism of Drug Action -Miscellaneous Mechanisms

Certain drugs do not act through any of the mechanisms already mentioned, they are categorized as miscellaneous. These include: Colchicines, …

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Mechanism of Drug Action -Drug Channel Interactions

In drug channel interaction, drug interfere with the flow of ions through the channels specific for these ions. These include …

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Mechanism of Drug Action -Drug Enzyme Interactions

Drug enzyme interaction is similar to drug receptor interactions. The drugs resemble the natural substrates, bind enzymes and cause change …

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Mechanism of Drug Action -Drug Receptor Interactions

Receptor: Macromolecules protein in nature which are target sites for drugs. Most drugs have to bind receptors to produce effects. …

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Mechanism of Drug Action -Chemical Mechanisms

In chemical mechanisms, drugs act by producing chemical reactions in the body. These include: Chemically acting antacids– NaHCO3 Chelating agents– …

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Mechanism of Drug Action -Physical Mechanisms

When the drug does not produce any chemical reaction or change in the cells of the body and the effect …

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Mechanism of Drug Action -An Introduction

All drugs bring about complex interactions with molecules of living systems. These actions, either physical or chemical, mainly act at …

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