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Pharmacology

Amphetamines

Amphetamines are indirectly acting. They act more powerfully on the CNS because in addition to noradrenaline, other biogenic amines are …

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Ephedrine

Ephedrine has mixed actions Source Natural ephedra plant. It can also be synthesized synthetically. Mechanism of Action Stimulates both alpha …

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Dobutamine

Receptor selectivity β1>β2>>>>α Dobutamine has a greater affinity for beta 1 receptors. It produces greater ionotropic effect than chronotropic effect. …

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Dopamine

The effect of dopamine on various receptors is concentration dependent D1=D2>>β>>α At lower concentration, only dopamine receptors are stimulated. At …

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Isoprenaline

Heavier the substitution on amino radical, greater is the beta activity. Isopropyl or propyl substitution in isoprenaline basically acts only …

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Noradrenaline

Receptor sensitivity in noradreanline is α1=α2,    β1>>β2 Thus its actions are somewhat different from that of adrenaline. Pharmacological Actions …

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Adrenaline

Adrenaline is a prototypical sympathomimetic drug (used as a template against which other drugs are compared); this is because it …

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Sympathomimetics

Symphathomimetics mimic the effects of sympathetic system. Two types of receptors are present: Alpha receptors Beta receptors All sympathomimetics act …

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Autonomic Nervous System –An Introduction

The central nervous system is divided into: Somatic system –voluntary Autonomic system –involuntary Autonomic nervous system is further classified into …

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Drug Dependence

Definition The WHO defines drug dependence as: “A state, psychic and sometimes  physical resulting  from taking a drug characterized by …

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