Undesirable or harmful effects which can occur at therapeutic doses and need a reduction of dose or drug withdrawal. Adverse … Read More »
Factors Modifying Action of Drugs
A multitude of host & environmental factors influence drug response. Understanding of these factors can guide choice of appropriate drug … Read More »
Mechanism of Drug Action -Miscellaneous Mechanisms
Certain drugs do not act through any of the mechanisms already mentioned, they are categorized as miscellaneous. These include: Colchicines, … Read More »
Mechanism of Drug Action -Drug Channel Interactions
In drug channel interaction, drug interfere with the flow of ions through the channels specific for these ions. These include … Read More »
Mechanism of Drug Action -Drug Enzyme Interactions
Drug enzyme interaction is similar to drug receptor interactions. The drugs resemble the natural substrates, bind enzymes and cause change … Read More »
Mechanism of Drug Action -Drug Receptor Interactions
Receptor: Macromolecules protein in nature which are target sites for drugs. Most drugs have to bind receptors to produce effects. … Read More »
Mechanism of Drug Action -Chemical Mechanisms
In chemical mechanisms, drugs act by producing chemical reactions in the body. These include: Chemically acting antacids– NaHCO3 Chelating agents– … Read More »
Mechanism of Drug Action -Physical Mechanisms
When the drug does not produce any chemical reaction or change in the cells of the body and the effect … Read More »
Mechanism of Drug Action -An Introduction
All drugs bring about complex interactions with molecules of living systems. These actions, either physical or chemical, mainly act at … Read More »
Clearance of Drug
Unit volume of blood which is cleared off a drug per unit time is known as clearance. Clearance is not … Read More »