howMed Know Yourself
Metronidazole is a prodrug itself, activated by reduction of nitro group. Structure Mechanism Of Action Protozoa get energy by ketoacids … Read More »
Anti Amoebic Drugs
These drugs are not only effective against amoebia but also against some others: Common diseases treated by these drugs A) … Read More »
Quinolones
Quinolones are the synthetic anti-microbial drugs. Structure of quinolones Contain quinalene nucleus. Two main groups are present: Compounds having fluorine … Read More »
Chloramphenicol
Chloramphenicol is a broad spectrum antibiotic and protein synthesis inhibitor. Source Isolated from cultures of streptomyces in Venezuela – 1947 … Read More »
Tetracyclines
Tetracyclines are a group of broad spectrum antibiotics whose general usefulness has been reduced with the onset of bacterial resistance. … Read More »
Macrolides
Macrolides are one of the most commonly used families of antibiotics, used to treat a wide variety of bacterial infections. … Read More »
Linezolid, Streptogramins, Fusidic Acid, Polymyxin, Bacitracin and Nitrofurantoin
Linezolid Antimicrobial agent synthetically produced. Chemistry – synthetic, belongs to oxazolidinones Mechanism of Action – binds 23S rRNA in 50S … Read More »
Beta Lactamase Inhibitors, Vancomycin and Clindamycin
Beta-lactamase Inhibitors Drugs having beta lactam molecules are not clinically given alone. There are 3 beta lactamase inhibitors: Clavulanic acid … Read More »
Monobactams and Carbapenims
Monobactams Monobactams are the beta lactam drugs. One in clinical use is: Aztreonam Monocyclic β-lactam ring Effective against aerobic gram … Read More »
Aminoglycosides
Important group discovered after penicillin. 1st member discovered was Streptomycin, which was discovered from mold, streptomycis. A large number of … Read More »