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Pharmacology

Metronidazole

Metronidazole is a prodrug itself, activated by reduction of nitro group. Structure Mechanism Of Action Protozoa get energy by ketoacids …

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Anti Amoebic Drugs

These drugs are not only effective against amoebia but also against some others: Common diseases treated by these drugs A)    …

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Quinolones

Quinolones are the synthetic anti-microbial drugs. Structure of quinolones Contain quinalene nucleus. Two main groups are present: Compounds having fluorine …

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Chloramphenicol

Chloramphenicol is a broad spectrum antibiotic and protein synthesis inhibitor. Source Isolated from cultures of streptomyces  in Venezuela – 1947 …

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Tetracyclines

Tetracyclines are a group of broad spectrum antibiotics whose general usefulness has been reduced with the onset of bacterial resistance. …

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Macrolides

Macrolides are one of the most commonly used families of antibiotics, used to treat a wide variety of bacterial infections. …

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Linezolid, Streptogramins, Fusidic Acid, Polymyxin, Bacitracin and Nitrofurantoin

Linezolid Antimicrobial agent synthetically produced. Chemistry – synthetic, belongs to oxazolidinones Mechanism of Action – binds 23S rRNA in 50S …

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Beta Lactamase Inhibitors, Vancomycin and Clindamycin

Beta-lactamase Inhibitors Drugs having beta lactam molecules are not clinically given alone. There are 3 beta lactamase inhibitors: Clavulanic acid …

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Monobactams and Carbapenims

Monobactams Monobactams are the beta lactam drugs. One in clinical use is: Aztreonam Monocyclic β-lactam ring Effective against aerobic gram …

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Aminoglycosides

Important group discovered after penicillin. 1st member discovered was Streptomycin, which was discovered from mold, streptomycis. A large number of …

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