Drugs Acting on Autonomic Nervous System

Autonomic Nervous System -An Introduction

Sympathomimetics

• Adrenaline
• Noradrenaline
• Isoprenaline
• Dopamine
• Doubutamine
• Ephedrine
• Amphetamines
• Phenyl Ephrine
• Salbutamol/Terbutaline

Beta Adrenoceptor Blockers

Alpha Adrenergic Blockers

• Phentolamine
• Phenoxy benzamine
• Prazosin
• Terazosin, Tamsulosin and Yohimbine

Ergot Alkaloids

• Bromocriptine
• Ergotamine vs Ergometrine

Parasympathomimetic Drugs

• Acetylcholine
• Carbachol
• Methacholine
• Bethancechol
• Muscarine and Pilocarpine
• Nicotine and Lobeline

Anticholinesterases

• Neostigmine
• Physostigmine
• Pyridostigmine, Edrophonium and Echothiophate

Organophosphate Poisoning and Management

Anticholinergic Drugs

Adrenergic Neuron Blockers and Guanethidine

• Reserpine
• Bretylium

Central Sympathoplegics and Alpha Methyl Dopa

• Clonidine
• Apraclonidine

Skeletal Muscle Relaxants

• Tubocurarine -Non Depolarizing Neuromuscular Blocker
• Atracurium, Cisatracurium, Gallamine and Steroid Derivatives -Non Depolarizing Neuromuscular Blockers
• Suxamethonium -Depolarizing Neuromuscular Blocker
• Factors affecting actions of Neuromuscular blockers
• Benzodiazepines as Centrally Acting Skeletal Muscle Relaxants
• Baclofen and Progabide -GABA Analogues
• Mephenesin and Meprobamate -Propandiol Derivatives
• Cyclobenzaprine, Orphenadrine and Tizanidine
• Dantrolene -Directly Acting Skeletal Muscle Relaxant