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Pasteurella Multocida

Pasteurella multocida is a gram negative coccobacillus, which is non-motile and pencillin sensitive, responsible for causing zoonotic infections.

Pasteurella are part of normal flora found in mouth of domestic cats and dogs. They are transmitted by biting.


Pathogenesis is not fully understood. Capsule has anti phagocytic properties. Endotoxin is produced but there is no exotoxin.

Virulence factors:
•    Endotoxin – lipopolysacchide
•    Capsule

Predisposing factors:
•    Sutured animal bites
•    Immunocompromised patients

Clinical symptoms:

•    Rapidly spreading cellulitis at the site of animal bite
•    Local wound infection
•    Lymphadenitis
•    Sub acute to chronic infections of lower respiratory tract

Lab diagnosis:

•    Sample from wound site

•    Gram negative rods
•    Short
•    Encapsulated
•    Bipolar staining

Pasteurella multocida, depicted using Gram stain technique
Pasteurella multocida, depicted using Gram stain technique

Serological test:
•    PCR


Penicillin G or ampicillin to prevent P. multocida infection when bitten.

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