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Pharmacology

How the pain reliever Tramadol works

tramadol

Tramadol is the best medication to relieve chronic pain Tramadol is an effective narcotic (opiate) analgesic prescribed to relieve moderate …

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Piperazine Citrate and Diethylcarbamazine -Antihelminthic Drugs

Ascaris

The article is a continuation of basics of antihelminthics. General Adverse Drugs Reactions  of Antihelminthics 1. Intestinal Actions Intestinal actions …

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Vinca Alkaloids, Taxanes, Epipodophyllotoxins, Camptothecins, Hormones, Anti-hormones, Asparaginase, Monoclonal Antibodies and Cytokines

Drugs

Vinca Alkaloids Mitotic spindle poisons. Vincristine is obtained from Vinca rosea Mechanism of Action – dimeric form, bind tubulin to …

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Methotrexate, 5-Fluorouracil, Purine Antagonists and Antibiotics Used in Cancer Chemotherapy

Drugs

Anti-Metabolites Anti metabolites are used to inhibit different metabolic pathways, as rate of metabolism and required metabolites are much higher …

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Alkylating Agents

oral drugs

Alkylating agents are the broad spectrum agennts. Chemistry Different reactive moiety: Bis (chloroethyl) amine / ethyleneimine / nitrosourea, responsible for …

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Cancer chemotherapy -An Introduction

drugs3

Cancer chemotherapy includes the drugs used to treat neoplasms, tumors or cancers. These include: Antineoplastic agents Anticancer drugs Cytotoxic drugs …

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Artemisinin, Lumefantrine, Mefloquine, Primaquine, Atovaquone, Proguanil and Pyrimethamine

Mefloquine structure

Qinghaosu (Artemisinin) Derivatives are the most novel and recently introduced. Now highly recommended. These drugs are artemisinin derivatives, discovered by …

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Quinine and Quinidine

Drugs obtained from Alkaloids  Quinine Alkaloids from Cinchona Two drugs are obtained: Quinine Quinidine Source & History Chief alkaloid of …

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Chloroquine

Chloroquine is one of the oldest anti-malarial agent, effectively used in malarial infections. P. falciparum and vivax are the sensitive …

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Anti Malarial Drugs

Different anti-malarial drugs are designed to target different steps in life cycle of plasmodium. Malaria is cause by four species …

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