howMed Know Yourself
Unit volume of blood which is cleared off a drug per unit time is known as clearance. Clearance is not … Read More »
Excretion of Drug
When drugs are taken in, they should be eliminated as well, as we do not want their action to continue … Read More »
Elimination of Drug
The irreversible shift of a drug from one part of the body to other part of system is known as … Read More »
Factors affecting Biotransformation
Biotransformation is significantly affected by a number of factors, these include: 1. Enzyme Induction: When drugs given over prolonged period … Read More »
Prodrugs
Prodrugs contain parent drug compounds in inactive form. Active specie is required to be carried to the site of action. … Read More »
Biotransformation of Xenobiotics
“Enzymatic modification of the drug occurring within the living organisms or chemical transformation a drug goes through in living organisms … Read More »
Plasma Half Life of Drugs
Onset, duration and intensity of effect of drug depends on the rate of absorption, distribution and elimination (biotransformation, excretion). In … Read More »
A case of Myasthenia Gravis
Case Scenario Mrs. Jameel, 45 years of age, is a housewife. Since last month she was feeling fatigue of shoulder … Read More »
A Case of Penicillin Drug Allergy
Case Scenario: A young female, 26 years old primae underwent C/S. Both mother and baby were clinically stable. She was … Read More »
Bioavailability of Drugs
Fraction of the dose of a drug contained in any dosage form that reaches the systemic circulation in unchanged or … Read More »
