Helicobacter pylori is a gram- negative rod, curved in shape and motile with the help of flagellum.
Route of Entry
- Person to person transmission
- Not isolated from food, water, stool or animals
- Chronic NSAID’s users
- Bad hygiene
- Use of proton pump inhibitors
- Peptic ulcers
- Recurrent upper abdominal pain
- No bacteremia or disseminated disease
- MALT ( mucosal associated lymphyd tissues )
• Stool -antigens are detected
• Gastric biopsy
Following features are observed under microscope:
• Gram- negative rods
• Curved in shape
• Flagellum present
- Microaerophilic organisms
- Gram – stain is used for gastric biopsy
- Gastric mucosa is cultured on improved perston blood-free medium. They are urease positive and show grey colonies.
- Blood agar -slightly beta hemolytic colonies are formed.
- Latex agglutination test
Two antibiotics plus an agent to lower acidity.