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Beta Lactamase Inhibitors, Vancomycin and Clindamycin

Beta-lactamase Inhibitors Drugs having beta lactam molecules are not clinically given alone. There are 3 beta lactamase inhibitors: Clavulanic acid …

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Monobactams and Carbapenims

Monobactams Monobactams are the beta lactam drugs. One in clinical use is: Aztreonam Monocyclic β-lactam ring Effective against aerobic gram …

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Aminoglycosides

Important group discovered after penicillin. 1st member discovered was Streptomycin, which was discovered from mold, streptomycis. A large number of …

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Cephalosporins

Cephalosporins are the derivatives from fungus cephalosporium, cultured near sea. Classification Classified into four generations depending upon antibacterial spectrum. 1st …

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Penicillins

Penicillins have made revolution in chemotherapy. They were discovered in 1929 by Alexander Fleming. He noticed colony of Staphylococci, which …

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Trimethoprim and Co-trimoxazole

Main problem with sulphonamides is that of resistance. Thus uses are declining. They are used in combination. Co-trimoxazole is combination …

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Sulfonamides

Sulfonamides were the first antimicrobial agents discovered and used. A group of scientists working on different dyes found a compound …

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Chemotherapy –An Introduction

Antimicrobial Drugs Antimicrobial drugs are the greatest contribution of 20th century to therapeutics Advent has changed the out look of …

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Oral Anti Diabetic Drugs

Sulfonylureas Ist Generation Tolbutamide Acetohexamide Chlorpropamide 2nd Generation Glibenclamide (glyburide) Glipizide Glimepiride Meglitinide Repaglinide D-Phenyl alanine Derivative Nateglinide Biguanide Metformin …

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Diabetes Mellitus and Insulin

Diabetes Mellitus Derived from Greek word diabainain: to pass through It is a state of high glucose levels which may …

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