howMed Know Yourself
The article is a continuation of basics of antihelminthics. General Adverse Drugs Reactions of Antihelminthics 1. Intestinal Actions Intestinal actions … Read More »
Piperazine Citrate and Diethylcarbamazine -Antihelminthic Drugs
Vinca Alkaloids, Taxanes, Epipodophyllotoxins, Camptothecins, Hormones, Anti-hormones, Asparaginase, Monoclonal Antibodies and Cytokines
Vinca Alkaloids Mitotic spindle poisons. Vincristine is obtained from Vinca rosea Mechanism of Action – dimeric form, bind tubulin to … Read More »
Methotrexate, 5-Fluorouracil, Purine Antagonists and Antibiotics Used in Cancer Chemotherapy
Anti-Metabolites Anti metabolites are used to inhibit different metabolic pathways, as rate of metabolism and required metabolites are much higher … Read More »
Alkylating Agents
Alkylating agents are the broad spectrum agennts. Chemistry Different reactive moiety: Bis (chloroethyl) amine / ethyleneimine / nitrosourea, responsible for … Read More »
Cancer chemotherapy -An Introduction
Cancer chemotherapy includes the drugs used to treat neoplasms, tumors or cancers. These include: Antineoplastic agents Anticancer drugs Cytotoxic drugs … Read More »
Artemisinin, Lumefantrine, Mefloquine, Primaquine, Atovaquone, Proguanil and Pyrimethamine
Qinghaosu (Artemisinin) Derivatives are the most novel and recently introduced. Now highly recommended. These drugs are artemisinin derivatives, discovered by … Read More »
Quinine and Quinidine
Drugs obtained from Alkaloids Quinine Alkaloids from Cinchona Two drugs are obtained: Quinine Quinidine Source & History Chief alkaloid of … Read More »
Chloroquine
Chloroquine is one of the oldest anti-malarial agent, effectively used in malarial infections. P. falciparum and vivax are the sensitive … Read More »
Anti Malarial Drugs
Different anti-malarial drugs are designed to target different steps in life cycle of plasmodium. Malaria is cause by four species … Read More »
Anti Hepatitis Drugs
Hepatitis is the inflammation of liver cells, caused by drugs, toxins, organisms. A number of viruses are more prone to … Read More »