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Cell Response to Reversible Injury

In response to injury, cells respond by:


Ability of normal cell to maintain steady state.


Adaptations are reversible, functional & structural changes to stress & noxious stimuli, which allow cells to live & continue to function.


Increase in size of cells


Increase in number of cells


Decrease in size of cells


Change in phenotype of cell

Thus, the cells respond by changes in their:

–    Size
–    Number
–    Shape (phenotype)
–    Metabolic activity
–    Functions

Cellular Adaptation

After non lethal injury cells may adapt to protect themselves. They may adapt by:

1.    Growth
–    Hyperplasia; hypoplasia
–    Hypertrophy; atrophy
–    Metaplasia; dysplasia.

2.    Degenerations (accumulations)
–    Hydropic change
–    Fatty change
–    Hyaline change
–    Pigment strorage-wear & tear

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