Classification of Tumors of Esophagus

Tumors of esophagus may be classified, based on histological features, into:

1.    Epithelial tumors:

a.    Squamous cell papilloma
b.    Intraepithelial neoplasia

• Squamous
• Glandular (Adenoma)

c.    Carcinoma:

• Squamous cell carcinoma
• Verrucous (Squamous) carcinoma
• Spindle cell (Squamous) carcinoma
• Adenocarcinoma
• Adenosquamous carcinoma
• Mucoepidermal carcinoma
• Adenoid cystic carcinoma
• Small cell carcinoma
• Undifferentiated carcinoma
• Other

d.    Carcinoid tumour

2.    Non-Epithelial tumors:

a.    Leiomyoma
b.    Lipoma
c.    Granular cell tumors
d.    Gastrointestinal stromal tumors

• Benign
• Uncertain malignant potential
• Malignant

e.    Leiomyosarcoma
f.    Rhabdomyosarcoma
g.    Kaposi’s sarcoma
h.    Malignant melanoma
i.    Others

3.    Secondary tumors