Thyroid hormones widespread and fundamental metabolic effects has evidence in the major clinical signs and symptoms commonly found in patients, presenting with either hypothyroidism or hyperthyroidism.
|
Hypothyroidism |
Hyperthyroidism |
|
Weight gain |
Weight loss |
|
Poor appetite, weight loss |
Increases appetite |
|
Mental/physical slowness |
Labile emotions |
|
Constipation |
Diarrhoea |
|
Cold intolerance |
Heart intolerance |
|
Bradycardia |
Tachycardia |
|
Dry skin |
Warm moist skin |
|
Slow ankle jerk relaxation |
Fine finger tremor |
|
Menstrual abnormalities |
Menstrual abnormalities |
Causes of Increase in Thyroid Hormones
| 1. Free thyroxine | |
| Thyroid disease |
|
| Iatrogenic |
|
| Other |
|
| 2. Total thyroxine | |
| Increases TBG |
|
| Thyroxine autoantibodies | |
| Familial dysalbuminaemic hyperthyroxinaemia | |
Causes of Decrease in Thyroid Hormones
| 1. Hypothyroidism |
|
(Hashimoto’s disease) |
| 2. Reduced binding sites |
|
|
|
|
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