howMed Know Yourself
Macrolides are one of the most commonly used families of antibiotics, used to treat a wide variety of bacterial infections. … Read More »
Linezolid, Streptogramins, Fusidic Acid, Polymyxin, Bacitracin and Nitrofurantoin
Linezolid Antimicrobial agent synthetically produced. Chemistry – synthetic, belongs to oxazolidinones Mechanism of Action – binds 23S rRNA in 50S … Read More »
Beta Lactamase Inhibitors, Vancomycin and Clindamycin
Beta-lactamase Inhibitors Drugs having beta lactam molecules are not clinically given alone. There are 3 beta lactamase inhibitors: Clavulanic acid … Read More »
Monobactams and Carbapenims
Monobactams Monobactams are the beta lactam drugs. One in clinical use is: Aztreonam Monocyclic β-lactam ring Effective against aerobic gram … Read More »
Aminoglycosides
Important group discovered after penicillin. 1st member discovered was Streptomycin, which was discovered from mold, streptomycis. A large number of … Read More »
Cephalosporins
Cephalosporins are the derivatives from fungus cephalosporium, cultured near sea. Classification Classified into four generations depending upon antibacterial spectrum. 1st … Read More »
Penicillins
Penicillins have made revolution in chemotherapy. They were discovered in 1929 by Alexander Fleming. He noticed colony of Staphylococci, which … Read More »
Trimethoprim and Co-trimoxazole
Main problem with sulphonamides is that of resistance. Thus uses are declining. They are used in combination. Co-trimoxazole is combination … Read More »
Sulfonamides
Sulfonamides were the first antimicrobial agents discovered and used. A group of scientists working on different dyes found a compound … Read More »
Chemotherapy –An Introduction
Antimicrobial Drugs Antimicrobial drugs are the greatest contribution of 20th century to therapeutics Advent has changed the out look of … Read More »