Cell Response to Reversible Injury

In response to injury, cells respond by:

Homeostasis:

Ability of normal cell to maintain steady state.

Adaptations:

Adaptations are reversible, functional & structural changes to stress & noxious stimuli, which allow cells to live & continue to function.

Hypertrophy:

Increase in size of cells

Hyperplasia:

Increase in number of cells

Atrophy:

Decrease in size of cells

Metaplasia:

Change in phenotype of cell

Thus, the cells respond by changes in their:

–    Size
–    Number
–    Shape (phenotype)
–    Metabolic activity
–    Functions

Cellular Adaptation

After non lethal injury cells may adapt to protect themselves. They may adapt by:

1.    Growth
–    Hyperplasia; hypoplasia
–    Hypertrophy; atrophy
–    Metaplasia; dysplasia.

2.    Degenerations (accumulations)
–    Hydropic change
–    Fatty change
–    Hyaline change
–    Pigment strorage-wear & tear